منابع مشابه
Good Housekeeping
In this issue of Neuron, Tani et al. (2014) revisit a disputed issue where biochemical and physiological data have provided conflicting results. Using a novel stimulation protocol, the authors isolate the contribution of the glutamate-glutamine cycle to excitatory synaptic transmission.
متن کاملGood housekeeping maintains a healthy liver
Good housekeeping maintains a healthy liver S nider et al. report that differential expression of two key metabolic enzymes may explain why some people are more susceptible to liver damage. Some forms of liver disease, particularly steatohepatitis, are marked by the formation of misfolded protein aggregates called Mallory-Denk bodies (MDBs). Not all patients display these aggregates, however, a...
متن کاملHousehold chemicals: good housekeeping or occupational hazard?
I n the Western world the role of air pollution in the initiation of respiratory disease in children is contentious [1]. There is good evidence that air pollution can trigger symptoms in susceptible children but its contribution to the pathogenesis of childhood respiratory disorders, such as asthma, remains unclear. There has been considerable interest in traffic-related pollutants and studies ...
متن کاملIs Good Housekeeping the Key to Motor Neuron Survival?
Spinal muscular atrophy (SMA) is caused by a drastic reduction in the ubiquitously expressed SMN protein, which is critical for the correct assembly of the snRNP complexes required for RNA splicing. However, it is unclear why loss of SMN and altered snRNP assembly only seem to affect motor neurons. Reporting in this issue, Zhang et al. (2008) challenge prior assumptions about the housekeeping f...
متن کاملActive chromatin hub of the mouse alpha-globin locus forms in a transcription factory of clustered housekeeping genes.
RNA polymerases can be shared by a particular group of genes in a transcription "factory" in nuclei, where transcription may be coordinated in concert with the distribution of coexpressed genes in higher-eukaryote genomes. Moreover, gene expression can be modulated by regulatory elements working over a long distance. Here, we compared the conformation of a 130-kb chromatin region containing the...
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ژورنال
عنوان ژورنال: Scientific American
سال: 1918
ISSN: 0036-8733
DOI: 10.1038/scientificamerican09141918-208